Matthew Stafford tied a career high with five touchdown passes, three of them to Calvin Johnson, lifting the Detroit Lions to a 45-14 home rout of the Philadelphia Eagles on Thursday.

The Lions (4-7) have won three straight this season and three in a row in their annual U.S. Thanksgiving game.

The Eagles (4-7) are on a three-game losing streak. They have allowed at least 45 points in two straight games in one season for the first time in team history, according to STATS.

Stafford threw for more than 200 yards and three touchdowns without a turnover by halftime, helping the Lions lead 24-7. He finished 27 of 38 for 337 yards and threw five TDs for the fourth time in his career.

Eagles quarterback Mark Sanchez started in place of Sam Bradford, who was inactive with a shoulder injury. Sanchez completed 19 of 27 passes for 199 yards and two TDs.